My graduate research involved the development of several microscope technologies: light sheet, multiphoton, super-resolution, hyperspectral, and light field. These imaging technologies have a broad range of applications that span many levels of organization, from the dynamics of single molecules to whole-brain neural activity in behaving animals. At Princeton, I continue to develop new optical tools, with an eye toward using these tools to study the basic physical principles that govern gene expression. I’d like to understand how remarkably precise patterns in the early embryo arise from spatially complex, rapidly evolving molecular events.