Paul Francois: Geometric model in latent space for fly development

Mon, Nov 11, 2019, 12:00 pm
Speaker(s): 
Sponsor(s): 
CPBF an NSF PFC

I will describe a new approach that we are currently developing to describe developmental dynamics. We are using simple machine learning techniques to project the dynamics of the Drosophila gap genes onto a low dimensional space, allowing us to build "geometric" models. We uncover a relatively simple dynamics in latent space, where we identify two modes, which allows us to capture with very good precision the entire gap genes dynamics. We interpret the dominating mode as a "maternal" contribution, while another mode accounts for "networks" effects. I will also discuss implication for positional information encoding, and interpretation of mutants.

Melike Lakadamyali: Super-resolution imaging of chromatin structure and dynamics

Mon, Nov 25, 2019, 12:00 pm

Nucleosomes help structure chromosomes by compacting DNA into fibers.  Chromatin organization plays an important role for regulating gene...

Location: Joseph Henry Room Jadwin Hall

Damon Clark: Mechanisms underlying visual illusions in flies

Mon, Dec 2, 2019, 12:00 pm

Visual systems detect many features of natural scenes, including motion. Motion detection guides critical behaviors like hunting, evading...

Location: Joseph Henry Room Jadwin Hall

Adaptation

Fri, Dec 6, 2019, 9:30 am

Adaptation and Bayesian forecasting in biological systems
Thierry Mora, École Normale Supérieure and Princeton University...

Location: The Graduate Center, Segal Theater. 365 Fifth Avenue, between 34th and 35th Streets, in Manhattan

Hana El-Samad: Biological Feedback Control

Mon, Dec 9, 2019, 12:00 pm

Organisms are an evolutionary masterpiece of feedback control, featuring a mind-boggling capacity to self-correct.

Location: Joseph Henry Room Jadwin Hall

Navish Wadhwa: TBD

Mon, Dec 16, 2019, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Dmitry Rinberg: TBD

Mon, Jan 27, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Sven van Taeffelen: TBD

Mon, Feb 3, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Elizabeth Jerison: TBD

Mon, Feb 10, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Elizabeth Jerison: TBD

Mon, Feb 10, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Stephanie Palmer: TBD

Mon, Feb 17, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Andrew York: TBD

Mon, Feb 24, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Andreas Gahlman: TBD

Mon, Mar 9, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall