Biophysics Seminars

Zaida Luthey-Schulten: Modeling the minimal cell: Integration of experiments, theory, and simulations

Mon, Sep 23, 2019, 12:00 pm

JCVI-syn3A, a robust minimal cell with a 543 kbp genome and 493 genes, provides a versatile platform to study the principles of life (Breuer et al. eLife 2019). Using the vast amount of experimental information available on its precursor, Mycoplasma mycoides capri, we assembled a near-complete essential metabolic network with 98% of enzymatic...

Andrew Mugler: Physics of collective cell sensing

Mon, Sep 30, 2019, 12:00 pm

The physical limits to chemical sensing have been established and tested for single cells. However, recent experiments have demonstrated that cells can surpass these limits when they communicate. The theoretical limits to the precision of collective sensing are still poorly understood.

John Marko: TBD

Mon, Oct 14, 2019, 12:00 pm

 I will discuss studies of the mechanics and structure of metaphase chromosomes and nuclei extracted from mammalian cells using glass micropipettes.

Aleksandra Walczak: Response in immune repertories

Mon, Oct 21, 2019, 12:00 pm

The immune repertoire responds to a wide variety of pathogenic threats. Immune repertoire sequencing experiments give us insight into the composition of these repertoires. Since the functioning of the repertoire relies on statistical properties, statistical analysis is needed to identify responding clones.

Ashley Carter: DNA Folding in Sperm

Mon, Nov 4, 2019, 12:00 pm

In sperm, DNA is tightly compacted to create a small, hydrodynamic sperm head. This dramatic reorganization of the nucleus is carried out by protamine proteins that fold the DNA into loops and toroids.

Paul Francois: TBD

Mon, Nov 11, 2019, 12:00 pm

Marija Zanic: TBD

Mon, Nov 18, 2019, 12:00 pm

Melike Lakadamyali: Super-resolution imaging of cellular organization

Damon Clark: TBD

Mon, Dec 2, 2019, 12:00 pm

Hana El-Samad: TBD

Mon, Dec 9, 2019, 12:00 pm