Biophysics Seminars

Dmitry Rinberg: Cracking the olfactory code using behavior

Mon, Jan 27, 2020, 12:00 pm

Two of the most fundamental questions of sensory neuroscience are: 1) how is stimulus information represented by neuronal activity? and 2) what features of this activity are read out to guide behavior? The first question has been the subject of a large body of work across different sensory modalities.

Sven van Teeffelen: Control of cell volume in rod-shaped bacteria

Mon, Feb 3, 2020, 12:00 pm

Bacteria exhibit a high degree of intracellular macromolecular crowding. To control the level of crowding cells must increase their volumes in response to the accumulation of biomass during growth. This coordination is fundamentally not understood in any cell type.

Elizabeth Jerison: Dynamics of adaptive immunity in zebrafish

Mon, Feb 10, 2020, 12:00 pm

The immune responses that defend us against pathogens are driven by stochastic processes amongst populations of cells. Enormous progress in immunology over the last few decades has identified most of the components of this complex system, including the cell types and the molecules used for communication.

Stephanie Palmer: How behavioral and evolutionary constraints sculpt early visual processing

Mon, Feb 17, 2020, 12:00 pm

While efficient coding has been a successful organizational principle in visual neuroscience, to make a more general theory behavioral, mechanistic, and even evolutionary constraints need to be added to this framework. In our work, we use a mix of known computational goals and detailed behavioral measurements to add constraints to the notion of...

Andrew York: TBD

Mon, Feb 24, 2020, 12:00 pm

Andreas Gahlmann: TBD

Mon, Mar 9, 2020, 12:00 pm

Allan Drummond: TBD

Mon, Mar 16, 2020, 12:00 pm

Na Ji: Imaging the brain at high spatiotemporal resolution

Mon, Mar 23, 2020, 12:00 pm

To understand computation in the brain, one needs to understand the input-output relationships for neural circuits and the anatomical and functional relationships of individual neurons therein. Optical microscopy has emerged as an ideal tool in this quest, as it is capable of recording the activity of neurons distributed over millimeter...

Stefano Allesina: TBD

Mon, Mar 30, 2020, 12:00 pm

Justin Kinney: Massively parallel assays, machine learning, and the biophysics of gene regulation

Mon, Apr 6, 2020, 12:00 pm

Gene expression in all organisms is controlled by short DNA and RNA sequences called cis-regulatory elements (CREs). Proteins in the cellular milieu bind to nucleic acid sequences present within CREs, interact with one another, and thus form macromolecular complexes that modulate the expression of nearby genes.