Andrew Mugler: Physics of collective cell sensing

Mon, Sep 30, 2019, 12:00 pm
Location: 
Joseph Henry Room Jadwin Hall
Speaker(s): 
Sponsor(s): 
CPBF an NSF PFC

The physical limits to chemical sensing have been established and tested for single cells. However, recent experiments have demonstrated that cells can surpass these limits when they communicate. The theoretical limits to the precision of collective sensing are still poorly understood. In this talk, I will discuss three types of cell-cell communication (short-range, long-range, and self-communication) and describe how they alter the physical limits for fundamental sensory tasks, including gradient sensing by epithelial organoids and flow sensing by metastatic cancer cells. This work extends the study of sensory limits to multicellular ensembles and lays the blueprint for a generic theory of collective sensing.

Andrew York: A bolt-on single-objective light-sheet design with uncompromised numerical aperture

Mon, Feb 24, 2020, 12:00 pm

Spinning disk confocal modules are “core facility friendly”; they insert conveniently between a commercial microscope base and camera, improve...

Location: Joseph Henry Room Jadwin Hall

Andreas Gahlman: TBD

Mon, Mar 9, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Andreas Gahlmann: Visualizing Bacterial Physiology at High Resolution using Single-Molecule Tracking and Lattice-Light Sheet Microscopy

Mon, Mar 9, 2020, 12:00 pm

Our lab develops new imaging approaches for visualizing bacterial physiology in relevant contexts: We use live-cell single-molecule localization...

Location: Joseph Henry Room Jadwin Hall

CPBF undergraduate outreach at CUNY

Fri, Mar 13, 2020, 1:30 pm to 4:00 pm
Location: Science Center (4102) at The Graduate Center. 365 Fifth Avenue, New York

Allan Drummond: Evolution of low-complexity protein regions implicated in biomolecular condensation

Na Ji: Imaging the brain at high spatiotemporal resolution

Mon, Mar 23, 2020, 12:00 pm

To understand computation in the brain, one needs to understand the input-output relationships for neural circuits and the anatomical and...

Location: Joseph Henry Room Jadwin Hall

Stefano Allesina: TBD

Mon, Mar 30, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Justin Kinney: Massively parallel assays, machine learning, and the biophysics of gene regulation

Mon, Apr 6, 2020, 12:00 pm

Gene expression in all organisms is controlled by short DNA and RNA sequences called cis-regulatory elements (CREs).

Location: Joseph Henry Room Jadwin Hall

David Van Valen: Deep learning for single cell biology

Mon, Apr 13, 2020, 12:00 pm

The study of living systems is challenging because of their high dimensionality, spatial and temporal heterogeneity, and high degree of...

Location: Joseph Henry Room Jadwin Hall

Problems in neural and cognitive computation

Fri, Apr 17, 2020, 10:00 am

Using food-caching birds to study the neuroscience of episodic memory
Dmitriy Aronov, Columbia University

Location: Segal Theater at The Graduate Center. 365 Fifth Avenue, New York

Seppe Kuehn: TBD

Mon, Apr 20, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall

Gurol Suel: TBD

Mon, Apr 27, 2020, 12:00 pm
Location: Joseph Henry Room Jadwin Hall