Nanofluidic devices, e.g. based on nanochannels or nanopores, are networks of fluid-filled structures on a chip with dimensions ~1-100 nm. These dimensions are on order of molecular length scales, giving rise to the ability to directly analyze, manipulate and confine single biomolecules. In this talk I will focus on two different…
Earth’s atmosphere provides a thin barrier to the severe conditions of space. Globally, terrestrial microorganisms from our planet’s surface move through and interact with the blanketing atmosphere, analogous to how marine microbes drift through vast oceans. Whereas a century of exploration has allowed oceanographers to characterize…
The interior of cells contains numerous components that need to be carefully organized in space to fulfill a wide range of biological functions. The most widespread form of intracellular compartments completely lack membranes. In the place of membranes, these compartments—so called biomolecular condensates—are sustained and segregated in space…
Recent advances in electrophysiology and optical imaging technologies enable recordings in behaving animals from hundreds or even thousands of neurons simultaneously. Since neural coding, computation, and communication rely on coordinated activity patterns across large cell populations, such data facilitate the study of the global structure of…